One-point population analysis and effect of osmolarity on detection of hetero-vancomycin-resistant Staphylococcus aureus

J Clin Microbiol. 2002 Apr;40(4):1493-5. doi: 10.1128/JCM.40.4.1493-1495.2002.

Abstract

The original screening test and one-point population analysis (OPPA) were compared for the detection of hetero-vancomycin-resistant Staphylococcus aureus, and the influence of osmolarity on those tests was evaluated. The positivity rates and the reproducibilities were similar for both tests. The addition of NaCl increased the MIC as well as the positivity rates for both tests and the reproducibility of OPPA.

Publication types

  • Evaluation Study

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Humans
  • Methicillin Resistance
  • Microbial Sensitivity Tests / methods
  • Osmolar Concentration
  • Sodium Chloride / pharmacology*
  • Staphylococcal Infections / microbiology
  • Staphylococcus aureus / drug effects*
  • Staphylococcus aureus / growth & development*
  • Vancomycin / pharmacology
  • Vancomycin Resistance*

Substances

  • Anti-Bacterial Agents
  • Sodium Chloride
  • Vancomycin