Repeated intervention for in-stent restenosis of the renal arteries

J Vasc Interv Radiol. 2002 Dec;13(12):1219-24. doi: 10.1016/s1051-0443(07)61968-x.

Abstract

Purpose: To assess the long-term technical success of repeated endovascular intervention in stenosed renal artery stents.

Materials and methods: Fifteen patients with stenoses >or=50% in a renal stent placed because of an ostial atherosclerotic renal artery stenosis were included in this study. In the presence of increased blood pressure or decreased renal function, the in-stent restenosis was treated with percutaneous transluminal angioplasty (PTA) in the stent or placement of a second stent if the stenosis was located too distally in the stent. The results of these repeat interventions were evaluated by angiography.

Results: The 15 patients had a total of 20 stenosed stents. Eighteen of these in-stent stenoses were treated with PTA and two were treated with placement of a second stent. Angiographic follow-up was available in 16 arteries, showing in-stent restenosis in four (25%; mean follow-up, 11 mo). The cumulative patency rates after repeat endoluminal intervention were 93% (95% CI: 80%-106%) and 76% (95% CI: 52%-101%) after 6 and 12 months, respectively. Renal function remained stable or improved in most patients (80%) after repeated intervention in the stent, and hypertension was classified as improved or cured in 47% of patients after 1 year.

Conclusion: Patients with stenosed renal artery stents can be treated successfully with PTA in a majority of cases, with a long-term success rate of 75% and stable renal function 1 year after repeated intervention.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Angioplasty, Balloon*
  • Equipment Failure
  • Female
  • Humans
  • Kidney / blood supply
  • Kidney / physiopathology
  • Kidney / surgery
  • Male
  • Middle Aged
  • Radiography, Interventional
  • Recurrence
  • Renal Artery Obstruction / diagnostic imaging
  • Renal Artery Obstruction / physiopathology
  • Renal Artery Obstruction / therapy*
  • Stents*
  • Time Factors
  • Treatment Outcome
  • Vascular Patency