Taxane-induced nail changes: incidence, clinical presentation and outcome

Ann Oncol. 2003 Feb;14(2):333-7. doi: 10.1093/annonc/mdg050.

Abstract

The clinical characteristics of nail changes in seven patients receiving taxane-containing chemotherapy are described. They include nail pigmentation, subungual hematoma, Beau's lines and onycholysis and subungual suppuration. The incidence of such changes (ranging from 0% to 44%) is reviewed from a Medline search of the literature.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents, Phytogenic / adverse effects*
  • Antineoplastic Agents, Phytogenic / therapeutic use
  • Docetaxel
  • Female
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Nail Diseases / chemically induced*
  • Nail Diseases / epidemiology
  • Paclitaxel / adverse effects*
  • Paclitaxel / analogs & derivatives*
  • Paclitaxel / therapeutic use*
  • Taxoids*

Substances

  • Antineoplastic Agents, Phytogenic
  • Taxoids
  • Docetaxel
  • Paclitaxel