[Cognitive decline and hypertension]

Arch Mal Coeur Vaiss. 2003 Jan;96(1):47-51.
[Article in French]

Abstract

The prevalence and incidence of degenerative and vascular dementia increase exponentially with age. Several studies in recent years have implicated hypertension as a risk factor not only for vascular dementia but also for degenerative dementia such as Alzheimer's disease. This is an important finding because it suggests that the treatment of hypertension could reduce the incidence of dementia. In particular, the results of the Syst-Eur study, showing that a calcium inhibitor, nitrendipine, could reduce not only the incidence of stroke but also that of dementia, should be confirmed.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adult
  • Aged
  • Aging
  • Antihypertensive Agents / therapeutic use
  • Clinical Trials as Topic
  • Cognition Disorders / etiology*
  • Cognition Disorders / prevention & control
  • Dementia, Vascular / etiology*
  • Dementia, Vascular / prevention & control
  • Humans
  • Hypertension / complications*
  • Hypertension / drug therapy
  • Middle Aged
  • Nitrendipine / therapeutic use
  • Risk Factors

Substances

  • Antihypertensive Agents
  • Nitrendipine