Off-pump right atrial thrombectomy for heparin-induced thrombocytopenia with thrombosis

Ann Thorac Surg. 2003 Aug;76(2):615-7. doi: 10.1016/s0003-4975(03)00159-0.

Abstract

This report describes a 72-year-old woman with atrial fibrillation who presented with lower extremity ischemia secondary to thromboembolism. After lower extremity thrombectomy, the patient developed heparin-induced thrombocytopenia with thrombosis (HITT). Her postoperative course was complicated by recurrent supraventricular and ventricular tachycardia, secondary to a mobile thrombus in the right atrium extending into the right ventricle. Because administration of heparin was contraindicated, the patient underwent off-pump right atrial thrombectomy during a brief period of inflow occlusion. Postoperatively, she was placed on lepirudin. Her platelet count normalized without any further thrombotic episodes, and she was discharged on warfarin.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Atrial Fibrillation / complications
  • Atrial Fibrillation / diagnosis
  • Cardiac Surgical Procedures / methods
  • Cardiopulmonary Bypass
  • Combined Modality Therapy
  • Female
  • Follow-Up Studies
  • Heart Atria / physiopathology
  • Heart Atria / surgery
  • Heparin / adverse effects*
  • Heparin / therapeutic use
  • Hirudins / analogs & derivatives*
  • Humans
  • Lower Extremity
  • Postoperative Period
  • Recombinant Proteins / therapeutic use
  • Risk Assessment
  • Thrombectomy / methods*
  • Thrombocytopenia / chemically induced*
  • Thromboembolism / complications
  • Thromboembolism / diagnosis
  • Thromboembolism / therapy*
  • Treatment Outcome
  • Venous Thrombosis / complications
  • Venous Thrombosis / diagnosis
  • Venous Thrombosis / therapy*

Substances

  • Hirudins
  • Recombinant Proteins
  • Heparin
  • lepirudin