Long term morbidity and mortality after kidney transplantation

Scand J Urol Nephrol. 1992;26(4):397-401. doi: 10.3109/00365599209181233.

Abstract

A cohort of 69 patients received a kidney transplant in the period 1963-1977. The mean observation time was 9.5 years. Accumulated follow-up time was 661.4 patients year. The mean (SE) 10-year survival was 55(5.9)%. Univariate analysis showed that female patients had poorer survival than male. Patients with a cadaveric donor had lower survival than those with a living donor. Also survival with different HLA-A,B match differed significantly. A multivariate analysis pinpointed nature of donor, cadaveric vs. living, as the sole independent predictor of mortality. Patients receiving a cadaveric kidney were on double (2.2) relative risk of mortality as compared to patients with a living donor. The major causes of death were infections during rejection treatment, and cardiovascular disease. Patients had low rates of morbidity. Our results showed satisfactory outcome of kidney transplantation.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cadaver
  • Cause of Death*
  • Female
  • Follow-Up Studies
  • Humans
  • Kidney Failure, Chronic / mortality
  • Kidney Failure, Chronic / surgery*
  • Kidney Transplantation / mortality*
  • Male
  • Middle Aged
  • Postoperative Complications / mortality*
  • Proportional Hazards Models
  • Reoperation
  • Risk Factors
  • Survival Rate