Objective: To observe hepatitis C virus (HCV) infection in blood recipients with hematonosis, and to investigate the significance of anti-HCV detection in the patients.
Methods: Anti-HCV was detected by enzyme-linked immunosorbent assay (ELISA) in 176 hematonosis patients before blood transfusion, the result of anti-HCV was compared with control (417 cases), and 95 blood recipients were followed up for 6-12 months after the transfusion.
Results: The positive rate of anti-HCV was 5.68% (10/176) in hematonosis patients before transfusion, higher than both in the control [0.72% (3/417), P < 0.01] and in the patients with general surgery [2.23% (21/942), P < 0.05], and no new infection case was found after the transfusion.
Conclusion: HCV infectionin in blood recipients with hematonosis should be paid attention to, and the detection of anti-HCV is necessary for patients before blood transfusion.