Palladium-catalyzed intermolecular coupling of aryl chlorides and sulfonamides under microwave irradiation

Org Lett. 2003 Nov 13;5(23):4373-6. doi: 10.1021/ol035655u.

Abstract

[reaction: see text] An efficient intermolecular N-arylation of sulfonamides with aryl chlorides is realized using palladium catalysis. The reaction proceeds under microwave irradiation at 180-200 degrees C for 10 min with 2-10 mol % of Pd catalyst in 32-85% isolated yields.