Ciprofloxacin-induced toxic epidermal necrolysis in a patient with systemic lupus erythematosus

Infection. 2003 Dec;31(6):428-9. doi: 10.1007/s15010-003-2128-3.

Abstract

Toxic epidermal necrolysis (TEN), or Lyell's syndrome, is a fulminant bullous dermatitis. TEN is often a drug-induced reaction and virtually any drug class appears capable of provoking it. We report here a case of TEN after administration of ciprofloxacin. Systemic lupus erythematosus (SLE) was suspected as a possible etiologic or modifying cofactor in TEN in this case.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Ciprofloxacin / adverse effects*
  • Ciprofloxacin / therapeutic use
  • Combined Modality Therapy
  • Disease Progression
  • Fatal Outcome
  • Female
  • Humans
  • Lupus Erythematosus, Systemic / diagnosis
  • Lupus Erythematosus, Systemic / drug therapy*
  • Netherlands
  • Risk Assessment
  • Severity of Illness Index
  • Stevens-Johnson Syndrome / etiology*
  • Stevens-Johnson Syndrome / physiopathology
  • Stevens-Johnson Syndrome / therapy

Substances

  • Ciprofloxacin