Abstract
Toxic epidermal necrolysis (TEN), or Lyell's syndrome, is a fulminant bullous dermatitis. TEN is often a drug-induced reaction and virtually any drug class appears capable of provoking it. We report here a case of TEN after administration of ciprofloxacin. Systemic lupus erythematosus (SLE) was suspected as a possible etiologic or modifying cofactor in TEN in this case.
MeSH terms
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Adult
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Ciprofloxacin / adverse effects*
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Ciprofloxacin / therapeutic use
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Combined Modality Therapy
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Disease Progression
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Fatal Outcome
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Female
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Humans
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Lupus Erythematosus, Systemic / diagnosis
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Lupus Erythematosus, Systemic / drug therapy*
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Netherlands
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Risk Assessment
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Severity of Illness Index
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Stevens-Johnson Syndrome / etiology*
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Stevens-Johnson Syndrome / physiopathology
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Stevens-Johnson Syndrome / therapy