Vulnerability of pulmonary capillaries during exercise

Exerc Sport Sci Rev. 2004 Jan;32(1):24-30. doi: 10.1097/00003677-200401000-00006.

Abstract

Pulmonary capillaries have a dilemma. Their walls must be extremely thin for efficient gas exchange, but be immensely strong to resist the mechanical stresses that develop during heavy exercise. Elite human athletes at maximal exercise develop changes in the structure of the capillary wall as evidenced by red blood cells in their alveoli. Racehorses routinely break their pulmonary capillaries while galloping.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Blood-Air Barrier*
  • Capillaries / pathology*
  • Capillaries / ultrastructure
  • Exercise / physiology*
  • Humans
  • Physical Exertion / physiology*
  • Pulmonary Circulation / physiology
  • Pulmonary Gas Exchange
  • Respiratory Mechanics
  • Risk Assessment
  • Sensitivity and Specificity
  • Stress, Mechanical