Abstract
We report a patient with lepromatous leprosy who developed a rare variant of type-2 lepra reaction, characterized by pustular lesions, on switching from WHO multi drug therapy (MDT) to ofloxacin-aided MDT.
MeSH terms
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Abscess / etiology
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Adult
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Drug Resistance, Bacterial
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Drug Therapy, Combination / therapeutic use
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Erythema Nodosum / chemically induced
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Erythema Nodosum / etiology*
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Erythema Nodosum / pathology
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Humans
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Leprostatic Agents / adverse effects*
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Leprostatic Agents / therapeutic use
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Leprosy, Lepromatous / complications*
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Leprosy, Lepromatous / drug therapy
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Leprosy, Lepromatous / microbiology
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Macrophages / pathology
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Male
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Melanins / analysis
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Minocycline / administration & dosage
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Minocycline / therapeutic use
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Mycobacterium tuberculosis / isolation & purification
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Neutrophils / pathology
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Ofloxacin / adverse effects*
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Ofloxacin / therapeutic use
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Rifampin / therapeutic use
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Tumor Necrosis Factor-alpha / metabolism
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Vasculitis / chemically induced
Substances
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Leprostatic Agents
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Melanins
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Tumor Necrosis Factor-alpha
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Ofloxacin
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Minocycline
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Rifampin