Geographic correlation between deprivation and risk of meningococcal disease: an ecological study

BMC Public Health. 2004 Jul 26:4:30. doi: 10.1186/1471-2458-4-30.

Abstract

Background: Meningitis caused by Neisseria meningitidis is a serious infection which is most common in young children and adolescents. This study investigated the relationships between the incidence and age distribution of meningococcal disease, and socioeconomic environment.

Methods: An ecological design was used, including mapping using a Geographical Information System (GIS) at census ward level.

Results: Incidence of meningococcal disease was highest in the most deprived wards, with a relative risk of 1.97 (1.55 - 2.51). Mapping revealed geographical coincidence of deprivation and meningococcal disease, particularly in urban areas. Two-thirds of the increased incidence was due to cases in the under fives.

Conclusions: The results suggest that area deprivation is a risk factor for meningococcal disease, and that its effects are seen most in young children.

MeSH terms

  • Adolescent
  • Age Distribution
  • Censuses
  • Child
  • Child, Preschool
  • Cluster Analysis
  • England / epidemiology
  • Geographic Information Systems*
  • Humans
  • Incidence
  • Infant
  • Meningococcal Infections / economics
  • Meningococcal Infections / epidemiology*
  • Meningococcal Infections / microbiology
  • Neisseria meningitidis / pathogenicity
  • Poisson Distribution
  • Poverty Areas*
  • Public Health Informatics
  • Risk Factors
  • Social Class
  • Topography, Medical / methods
  • Urban Health / statistics & numerical data