Eighty-one cases of advanced gastric cancer, who had been treated by intra-arterial infusion chemotherapy, were examined for complications related to catheter indwelling. Subjects consisted of 46 cases of aortic cannulation (via femoral artery, 29; via subclavian artery, 17) and 35 cases of hepatic cannulation (via laparotomy, 29; via subclavian a, 6). As the result, complications were more frequent in the cases via femoral (24.1%) and via laparotomy (41.4%), whereas there was only one case in subclavian route. Six cases (67%) of dislocations developed within one month after cannulation and occlusions (8 cases) were often found in cases of one shot or non-injection. In conclusion, cannulation via subclavian artery is an excellent method.