Rapid discontinuation of prednisone in higher-risk kidney transplant recipients

Khalid Khwaja; Massimo Asolati; James V Harmon; J Keith Melancon; Ty B Dunn; Kristen J Gillingham; Raja Kandaswamy; Abhinav Humar; Rainer W G Gruessner; William D Payne; John S Najarian; David L Dunn; David E R Sutherland; Arthur J Matas

doi:10.1097/01.tp.0000136964.59494.ff

Rapid discontinuation of prednisone in higher-risk kidney transplant recipients

Transplantation. 2004 Nov 15;78(9):1397-9. doi: 10.1097/01.tp.0000136964.59494.ff.

Authors

Khalid Khwaja¹, Massimo Asolati, James V Harmon, J Keith Melancon, Ty B Dunn, Kristen J Gillingham, Raja Kandaswamy, Abhinav Humar, Rainer W G Gruessner, William D Payne, John S Najarian, David L Dunn, David E R Sutherland, Arthur J Matas

Affiliation

¹ Department of Surgery, University of Minnesota, MN 55455, USA.

PMID: 15548981
DOI: 10.1097/01.tp.0000136964.59494.ff

Abstract

Prednisone-minimization protocols have been successful in low-risk recipients. We report on the use of a protocol incorporating rapid discontinuation of prednisone in a cohort of kidney transplant recipients (n = 79) at increased immunologic risk. Our data suggests that such recipients should not be excluded from prednisone-minimization protocols.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Humans
Immunosuppression Therapy*
Kidney Transplantation* / immunology
Kidney Transplantation* / mortality
Prednisone / administration & dosage*
Risk
Survival Rate

Substances

Prednisone

Grants and funding

DK 13083/DK/NIDDK NIH HHS/United States