Effect of antispastic agents (calcium antagonists and/or isosorbide dinitrate) on high-sensitivity C-reactive protein in patients with coronary vasospastic angina pectoris and no hemodynamically significant coronary artery disease

Am J Cardiol. 2005 Jan 1;95(1):84-7. doi: 10.1016/j.amjcard.2004.08.064.

Abstract

Levels of high-sensitivity C-reactive protein were measured before and after 3 months of treatment with antispastic agents (calcium antagonists and/or isosorbide dinitrate) in 27 patients who had coronary vasospastic angina pectoris and no hemodynamically significant coronary artery disease. Levels of high-sensitivity C-reactive protein decreased after treatment with antispastic agents.

MeSH terms

  • Angina Pectoris / drug therapy*
  • Angina Pectoris / etiology
  • Angina Pectoris / physiopathology*
  • C-Reactive Protein / drug effects*
  • Calcium Channel Blockers / pharmacology*
  • Calcium Channel Blockers / therapeutic use
  • Coronary Disease / complications
  • Coronary Disease / physiopathology
  • Coronary Vasospasm / complications
  • Coronary Vasospasm / drug therapy*
  • Female
  • Hemodynamics
  • Humans
  • Isosorbide Dinitrate / pharmacology*
  • Isosorbide Dinitrate / therapeutic use
  • Male
  • Middle Aged
  • Parasympatholytics / pharmacology*
  • Parasympatholytics / therapeutic use

Substances

  • Calcium Channel Blockers
  • Parasympatholytics
  • C-Reactive Protein
  • Isosorbide Dinitrate