Oral steroid regimens for idiopathic sudden sensorineural hearing loss

Otolaryngol Head Neck Surg. 2005 Jan;132(1):5-10. doi: 10.1016/j.otohns.2004.09.072.

Abstract

Objective: To determine hearing recovery in patients with idiopathic sudden hearing loss treated with varying amounts of oral steroids.

Study design and setting: A retrospective chart review (n = 75) in a tertiary care clinic examined sudden hearing loss patients treated with 1 60-mg prednisone taper, 1 course of steroid less than a 60-mg taper, or any 2 courses of oral steroid.

Results: Overall, 35% of the patients recovered a clinically significant amount of hearing. Recovery was associated with immediate treatment (within 2 weeks from onset), better hearing at the onset of treatment, and treatment with the higher dose of prednisone in patients with just 1 additional symptom (dizziness or tinnitus). Patients tended to continue to experience some recovery in hearing up to 4 months after treatment.

Conclusion: Immediate treatment of patients with unilateral idiopathic sudden hearing loss and additional symptoms (dizziness or tinnitus) with a 14-day course of 60 mg prednisone (with taper) is recommended.

Ebm rating: B-3.

MeSH terms

  • Administration, Oral
  • Female
  • Glucocorticoids / administration & dosage*
  • Hearing Loss, Sensorineural / complications
  • Hearing Loss, Sensorineural / drug therapy*
  • Hearing Loss, Sudden / complications
  • Hearing Loss, Sudden / drug therapy*
  • Humans
  • Male
  • Middle Aged
  • Prednisone / administration & dosage*
  • Retrospective Studies

Substances

  • Glucocorticoids
  • Prednisone