Photodynamic therapy and indocyanine green guided feeder vessel photocoagulation of choroidal neovascularization secondary to choroid rupture after blunt trauma

Graefes Arch Clin Exp Ophthalmol. 2005 Jan;243(1):68-71. doi: 10.1007/s00417-004-0964-1. Epub 2004 Aug 4.

Abstract

Purpose: To describe photodynamic therapy (PDT) and additional indocyanine green (ICG) guided feeder vessel photocoagulation as a treatment of choroidal neovascularization (CNV) secondary to choroidal rupture in case of blunt head trauma.

Design: Interventional case report.

Methods: A 61-year-old woman developed subfoveal CNV originating from a choroid tear 8 years after blunt head trauma. Four sessions of PDT were applied and an additional two consecutive sessions of selective ICG-guided feeder vessel photocoagulation conducted.

Results: Transient reduction of leakage and closure of feeder vessels could not prevent further growth of the CNV.

Conclusions: PDT reduced leakage temporarily and additional ICG-guided feeder vessel photocoagulation closed treated feeder vessel and CNV. New feeder vessel formation and growth of CNV in case of traumatic choroid rupture could not be treated effectively by these two laser treatment modalities to prevent severe deterioration of visual acuity.

Publication types

  • Case Reports

MeSH terms

  • Choroid / injuries*
  • Choroidal Neovascularization / drug therapy
  • Choroidal Neovascularization / etiology
  • Choroidal Neovascularization / surgery
  • Choroidal Neovascularization / therapy*
  • Coloring Agents*
  • Combined Modality Therapy
  • Female
  • Fluorescein Angiography
  • Humans
  • Indocyanine Green*
  • Laser Coagulation*
  • Middle Aged
  • Photochemotherapy*
  • Photosensitizing Agents / therapeutic use
  • Porphyrins / therapeutic use
  • Rupture
  • Verteporfin
  • Visual Acuity
  • Wounds, Nonpenetrating / complications*

Substances

  • Coloring Agents
  • Photosensitizing Agents
  • Porphyrins
  • Verteporfin
  • Indocyanine Green