The Cooperative Outcomes Group for ENT: a multicenter prospective cohort study on the effectiveness of medical and surgical treatment for patients with chronic rhinosinusitis

Otolaryngol Head Neck Surg. 2005 Feb;132(2):171-9. doi: 10.1016/j.otohns.2004.11.003.

Abstract

Objective: To assess outcomes for patients with chronic rhinosinusitis.

Study design and setting: Prospective, multicenter study; 31 otolaryngologists enrolled 276 adult patients with chronic rhinosinusitis; patients completed surveys at 3-month intervals, and physicians provided clinical and treatment data. The primary outcome measure was the Chronic Sinusitis Survey-Duration (CSS-D).

Results: One hundred seventeen adult patients completed 12-month follow-up. Most patients reported sinus symptoms lasting longer than 3 years (74%). Patients showed significant improvement (group P < 0.0001) in the CSS-D score at each follow-up interval. Baseline CSS-D ( P < 0.0001), surgical intervention ( P < 0.003), and Lund-McKay score ( P < 0.04) were predictive of clinical success in regression analysis.

Conclusions: Patients referred to an otolaryngologist have a severe sinus illness. Treatment by an otolaryngologist was associated with significant improvement in sinus-related symptoms.

Significance: The study demonstrated the feasibility of multicenter outcome studies in chronic rhinosinusitis and generated testable hypotheses for future investigation.

Ebm rating: C.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Chronic Disease
  • Female
  • Follow-Up Studies
  • Health Surveys
  • Humans
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care*
  • Prospective Studies
  • Quality of Life
  • Rhinitis / complications
  • Rhinitis / drug therapy*
  • Rhinitis / surgery*
  • Sinusitis / complications
  • Sinusitis / drug therapy*
  • Sinusitis / surgery*
  • Time Factors