Sustained viral suppression and immune recovery in HIV type 1-infected children after 4 years of highly active antiretroviral therapy

Clin Infect Dis. 2005 Feb 15;40(4):604-8. doi: 10.1086/427696. Epub 2005 Jan 25.

Abstract

We report the data from a long-term study of 31 human immunodeficiency virus type 1 (HIV-1)-infected children who were treated with highly active antiretroviral therapy. A high proportion of the children had undetectable HIV-1 RNA levels. CD4+ T cell counts recovered and remained stable. Adverse events were observed frequently but were mostly mild.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Antiretroviral Therapy, Highly Active / methods*
  • CD4 Lymphocyte Count
  • Child
  • Child, Preschool
  • Cohort Studies
  • Female
  • HIV Infections / drug therapy*
  • HIV Infections / immunology*
  • HIV Infections / virology
  • HIV-1 / drug effects*
  • Humans
  • Male
  • Prospective Studies
  • RNA, Viral / blood*
  • Time Factors
  • Treatment Outcome

Substances

  • RNA, Viral