UVB 311 nm tolerance of vitiligo skin increases with skin photo type

Acta Derm Venereol. 2005;85(1):24-6. doi: 10.1080/00015550410022203.

Abstract

It is assumed that skin is protected against sunburn by melanin. In patients with vitiligo, there are white patches in the normal pigmented skin. We noticed that there is a difference in burning capacity of these white patches between people with different skin types. With UVB 311 nm lamps, we irradiated both lesional and non-lesional skin with increasing doses in 33 patients with vitiligo, divided into 5 groups according to skin type (II-VI). Twenty-four hours later we assessed the minimal erythema dose and found a correlation between skin type and UV sensitivity in both lesional skin and normal skin. We suggest that there must be a protection mechanism, other than that offered by melanin pigmentation. The antioxidant status may play a role in this phenomenon.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Dose-Response Relationship, Radiation
  • Erythema / etiology*
  • Erythema / prevention & control
  • Female
  • Humans
  • Male
  • Middle Aged
  • Radiation Tolerance*
  • Skin Pigmentation / radiation effects*
  • Ultraviolet Rays / adverse effects*
  • Vitiligo / complications*