A new synthesis of dienone lactones using a combination of hypervalent iodine(III) reagent and heteropoly acid

Chem Commun (Camb). 2005 May 21:(19):2465-7. doi: 10.1039/b501792k. Epub 2005 Mar 24.

Abstract

The oxidation of non-phenolic alkanoic acid derivatives to oxygen heterocycles was investigated; a new oxidative route to dienone lactones has been developed using a combination of hypervalent iodine(III) reagent, phenyliodine(III) bis(trifluoroacetate)(PIFA), and heteropoly acid (HPA).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cyclization
  • Fluoroacetates*
  • Heterocyclic Compounds / chemical synthesis
  • Heterocyclic Compounds / chemistry
  • Indicators and Reagents
  • Iodine / chemistry*
  • Iodobenzenes
  • Lactones / chemistry*
  • Oxidation-Reduction
  • Trifluoroacetic Acid / chemistry

Substances

  • Fluoroacetates
  • Heterocyclic Compounds
  • Indicators and Reagents
  • Iodobenzenes
  • Lactones
  • phenyliodine(III) bis(trifluoroacetate)
  • Iodine
  • Trifluoroacetic Acid