The abandoned trials of pre-exposure prophylaxis for HIV: what went wrong?

PLoS Med. 2005 Sep;2(9):e234. doi: 10.1371/journal.pmed.0020234. Epub 2005 Jul 19.

Abstract

The dramatic protests that shut down trials of tenofovir as pre-exposure prophylaxis against HIV may prove damaging in our fight against the HIV pandemic.

MeSH terms

  • Adenine / analogs & derivatives*
  • Adenine / therapeutic use
  • Global Health
  • HIV Infections / prevention & control*
  • Health Knowledge, Attitudes, Practice
  • Humans
  • Organophosphonates / therapeutic use*
  • Patient Advocacy*
  • Public Opinion*
  • Randomized Controlled Trials as Topic
  • Research Design
  • Reverse Transcriptase Inhibitors / therapeutic use*
  • Tenofovir

Substances

  • Organophosphonates
  • Reverse Transcriptase Inhibitors
  • Tenofovir
  • Adenine