How does MYCN amplification make neuroblastomas behave aggressively? Still more questions than answers

Pediatr Blood Cancer. 2005 Dec;45(7):869-70. doi: 10.1002/pbc.20576.
No abstract available

Publication types

  • Comment

MeSH terms

  • Gene Amplification*
  • Gene Dosage*
  • Gene Expression Regulation, Neoplastic*
  • Humans
  • Inhibitor of Differentiation Protein 2 / genetics*
  • Inhibitor of Differentiation Protein 2 / metabolism
  • N-Myc Proto-Oncogene Protein
  • Neuroblastoma / genetics*
  • Neuroblastoma / metabolism
  • Neuroblastoma / pathology
  • Nuclear Proteins / genetics*
  • Nuclear Proteins / metabolism
  • Oncogene Proteins / genetics*
  • Oncogene Proteins / metabolism
  • Retinoblastoma Protein / genetics
  • Retinoblastoma Protein / metabolism

Substances

  • ID2 protein, human
  • Inhibitor of Differentiation Protein 2
  • MYCN protein, human
  • N-Myc Proto-Oncogene Protein
  • Nuclear Proteins
  • Oncogene Proteins
  • Retinoblastoma Protein