Breast cancer screening in women surviving Hodgkin disease

Am J Clin Oncol. 2006 Jun;29(3):258-66. doi: 10.1097/01.coc.0000209447.63640.5a.

Abstract

Objective: To inform female Hodgkin disease (HD) survivors, younger than 35 at diagnosis, of their increased risk for breast cancer and encourage them to seek breast cancer screening.

Methods: An evidence-based intervention, telephone counseling, was used in a pre-post test design, randomized trial with the control group being offered the intervention following the post-test. Women treated at Stanford University who received thoracic irradiation before age 35, alive and HD-free at last contact, were referred to the project (n = 471). Of 261 eligible women who could be located, 157 completed the pretest and were randomized (60% response rate) and 133 completed the post-test (85% retention rate).

Results: There was a positive intervention effect on mammography maintenance: the odds of being in maintenance at post-test compared with pretest were greater in the intervention group than in the control group [odds ratio (OR) = 3.6]. Women were more likely to be in mammography maintenance at pre- or post-test if at pretest they were married (OR = 5.7), employed (OR = 2.3), more worried about breast cancer (OR = 1.4 per unit of scale), or received an annual physical examination (OR = 2.2). Women under age 40 were much less likely to be in maintenance than were those age 45 and over (age 35-39, OR = 0.2; under age 35, OR = 0.07).

Conclusions: The findings indicate that providing risk information encourages cancer survivors to take health preventive actions. Telephone counseling is a method that can provide risk information and is easily transferable to settings where people seek health information, such as telephone information lines.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age of Onset
  • Breast Neoplasms / diagnostic imaging*
  • Breast Neoplasms / etiology
  • Counseling*
  • Female
  • Health Behavior
  • Hodgkin Disease* / radiotherapy
  • Humans
  • Mammography
  • Neoplasms, Radiation-Induced / diagnostic imaging
  • Patient Education as Topic*
  • Risk Factors
  • Survivors
  • Telephone