The 7th International Workshop on Clinical Pharmacology of HIV Therapy was held at the Alfa Corinthia Hotel in Lisbon, Portugal. Approximately 200 pharmacologists and other scientists interested in antiretroviral pharmacology were in attendance this year. The workshop invited five lecturers to speak on topics including priorities for HIV pharmacology research in developing countries, the role of modelling and simulation in antiviral drug development, hepatotoxic side effects of antiretrovirals, peptide CCR5 antagonists, and HIV pharmacoepidemiology. The workshop also convened round table discussions on the use of therapeutic drug monitoring including updated recommendations, penetration of antiretrovirals into the CNS and genital tract, and drug labelling for antiretroviral drugs under the new FDA format. In total, 87 abstracts were accepted for presentation at the meeting: 29 oral and 58 poster presentations. This article highlights select presentations from the workshop.