Pharmacodynamic studies on PPIs: look carefully at the country of origin

Dig Liver Dis. 2006 Nov;38(11):808-10. doi: 10.1016/j.dld.2006.07.006. Epub 2006 Sep 1.
No abstract available

Publication types

  • Comment

MeSH terms

  • 2-Pyridinylmethylsulfinylbenzimidazoles / administration & dosage*
  • Adult
  • Anti-Ulcer Agents / administration & dosage*
  • Aryl Hydrocarbon Hydroxylases / genetics*
  • Asian People* / genetics
  • Cytochrome P-450 CYP2C19
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Gastroesophageal Reflux / drug therapy*
  • Gastroesophageal Reflux / microbiology
  • Genotype
  • Helicobacter Infections / drug therapy
  • Helicobacter Infections / genetics
  • Helicobacter pylori*
  • Humans
  • Hydrogen-Ion Concentration
  • Japan
  • Mixed Function Oxygenases / genetics*
  • Polymorphism, Genetic
  • Proton Pump Inhibitors
  • Rabeprazole
  • Stomach / chemistry

Substances

  • 2-Pyridinylmethylsulfinylbenzimidazoles
  • Anti-Ulcer Agents
  • Proton Pump Inhibitors
  • Rabeprazole
  • Mixed Function Oxygenases
  • Aryl Hydrocarbon Hydroxylases
  • CYP2C19 protein, human
  • Cytochrome P-450 CYP2C19