Disseminated haemangioblastoma without evidence of the von Hippel-Lindau syndrome or haemangioblastomatosis--A case report and clinico-pathological correlation

Clin Neurol Neurosurg. 2007 Apr;109(3):305-10. doi: 10.1016/j.clineuro.2006.12.007. Epub 2007 Jan 23.

Abstract

A 71-year-old Caucasian female presented to our service with disseminated cranial and spinal haemangioblastomata but no other features to suggest the von Hippel-Lindau syndrome. We feel that this represents cellular dissemination through the cerebro-spinal fluid and may be an intermediate step to the development of frank haemangioblastomatosis. By comparing this presentation to that of other tumours we have suggested a potential pathological mechanism and have discussed its management.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Brain Neoplasms / cerebrospinal fluid
  • Brain Neoplasms / pathology*
  • Brain Neoplasms / surgery
  • Female
  • Hemangioblastoma / cerebrospinal fluid
  • Hemangioblastoma / pathology*
  • Hemangioblastoma / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Neoplasm Invasiveness
  • Neoplasms, Second Primary / pathology*
  • Neoplasms, Second Primary / surgery
  • Neurosurgical Procedures
  • von Hippel-Lindau Disease / diagnosis*