From September 1988 to September 1989 perineal puncture prostatography with 60% urografin was performed in 21 patients with the prostate enlargement. Prostatographic findings suggested that 15 patients had benign prostatic hyperplasia and 6 had prostatic cancer. The diagnosis had been histologically proved after prostatectomy in 19 cases. The procedure was easily and safely conducted at outpatient clinic without complications. We believe that prostatography is useful in differential diagnosis of prostatic diseases and in selecting operative methods.