Pyoderma facial (PF) is a sudden severe eruption of pustules and cystic swellings which may be interconnected by sinuses. It affects mainly adult women. We report the case of a 21-year-old woman presenting with sudden onset of coalescing nodules and abscesses on the face, with mild systemic disturbance. She also had erythema nodosum (EN)-like lesions on the legs. To the best of our knowledge, this is the first reported case of PF associated with EN.