Pretherapeutic staging of recurrent laryngeal carcinoma: clinical findings and imaging studies compared with histopathology

Otolaryngol Head Neck Surg. 2007 Sep;137(3):487-91. doi: 10.1016/j.otohns.2007.03.022.

Abstract

Objective: To assess the accuracy of preoperative imaging studies and clinical and endoscopic examinations for recurrent laryngeal carcinoma evaluation.

Study design and setting: A retrospective comparative study was performed at a university department on 42 recurrent laryngeal carcinomas. Surgical specimens were cut into whole-organ slices. Histologic findings were compared with the findings of the different preoperative diagnostic modalities.

Results: The craniocaudal tumor spread was correctly evaluated by endoscopy and imaging studies in 52% and 24%, respectively, and the contralateral tumor spread in 50% and 52%, respectively. The sensitivity, specificity, and accuracy for detection of tumor infiltration of the thyroid was 48%, 88%, and 64% and of the cricoid 47%, 80%, and 67%. The accuracy of recurrent tumor classification (crT) was 50%; most tumors were underclassified.

Conclusion: The inadequately evaluated tumor spread and the inadequately classified recurrent tumors were underestimated and underclassified in most cases, respectively.

Publication types

  • Comparative Study

MeSH terms

  • Carcinoma / diagnostic imaging
  • Carcinoma / pathology*
  • Carcinoma / surgery
  • Humans
  • Laryngeal Neoplasms / diagnostic imaging
  • Laryngeal Neoplasms / pathology*
  • Laryngeal Neoplasms / surgery
  • Laryngoscopy*
  • Magnetic Resonance Imaging*
  • Neoplasm Recurrence, Local / diagnostic imaging
  • Neoplasm Recurrence, Local / pathology*
  • Neoplasm Recurrence, Local / surgery
  • Neoplasm Staging
  • Predictive Value of Tests
  • Preoperative Care
  • Reproducibility of Results
  • Retrospective Studies
  • Tomography, X-Ray Computed*