Construction of the building of contemporary Second Surgical Clinic of the cardiovascular Surgery was finished in 1921. Since the first intention to erect a new building for the Clinics of Gynaecology to its accomplishment full 46 years had elapsed. Since 1941 the building was used first by the German and later the Czech Clinics of Dermatovenerology and since 1955 it belonged to the Second Surgical Clinic of the General Teaching Hospital. In 1966 specialization of the clinic turned to the cardiovascular surgery. In relation to that, the building was to a great extent reconstructed.