Abstract
Several cDNAs of enzymes catalyzing biosynthetic pathways of plant-derived alkaloids have recently been heterologously expressed, and the production of appropriate enzymes from ajmaline and tropane alkaloid biosynthesis in bacteria allows their crystallization. This review describes the architecture of these enzymes with and without their ligands.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Biological Products* / biosynthesis
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Biological Products* / chemistry
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Biological Products* / isolation & purification
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Biological Products* / pharmacology
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Indole Alkaloids* / chemical synthesis
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Indole Alkaloids* / chemistry
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Indole Alkaloids* / isolation & purification
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Indole Alkaloids* / pharmacology
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Molecular Structure
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Plants, Medicinal / chemistry*
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Plants, Medicinal / enzymology
Substances
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Biological Products
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Indole Alkaloids