Antibody-based HIV-1 vaccines: recent developments and future directions

PLoS Med. 2007 Dec;4(12):e348. doi: 10.1371/journal.pmed.0040348.

Abstract

The authors discuss humoral immune responses to HIV and approaches to designing vaccines that induce viral neutralizing and other potentially protective antibodies.

Publication types

  • Congress

MeSH terms

  • AIDS Vaccines / chemistry
  • AIDS Vaccines / immunology*
  • Animals
  • Antibody Formation*
  • B-Lymphocytes / immunology
  • Complement System Proteins / immunology
  • Drug Design
  • Epitope Mapping
  • HIV Antibodies / blood*
  • HIV Antibodies / chemistry
  • HIV Antigens / immunology*
  • HIV Infections / immunology
  • HIV Infections / prevention & control*
  • HIV Infections / virology
  • HIV-1 / immunology*
  • Humans
  • Neutralization Tests / standards
  • Protein Conformation
  • Quality Control
  • Receptors, Fc / immunology
  • Reproducibility of Results

Substances

  • AIDS Vaccines
  • HIV Antibodies
  • HIV Antigens
  • Receptors, Fc
  • Complement System Proteins