Abstract
A 78-year-old Japanese man who had clinical symptoms and a flu-like illness with fever, chills, diarrhea, and arthralgia had traveled to Cambodia and Khabarovsk, Russia, before the onset of symptoms and illness. He had been bitten by an Ixodes persulcatus tick in which the DNA of Borrelia valaisiana was detected. The patient's symptoms improved rapidly after treatment with minocycline. Serologic examination detected antibodies to Lyme disease Borrelia. An flaB polymerase chain reaction with the patient's plasma amplified a DNA fragment similar to that of B. valaisiana.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Animals
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Anti-Bacterial Agents / administration & dosage
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Borrelia / classification
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Borrelia / genetics
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Borrelia / immunology
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Borrelia / isolation & purification*
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Borrelia Infections / diagnosis
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Borrelia Infections / microbiology*
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Flagellin / genetics
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Humans
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Immunoglobulin M / blood
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Immunoglobulin M / metabolism
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Ixodes / classification
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Ixodes / genetics
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Japan
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Male
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Minocycline / administration & dosage
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RNA, Ribosomal, 16S / genetics
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Sequence Homology, Nucleic Acid
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Travel*
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Treatment Outcome
Substances
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Anti-Bacterial Agents
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Immunoglobulin M
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RNA, Ribosomal, 16S
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Flagellin
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flaB flagellin
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Minocycline