Abstract
Fluoroquinolone- and methicillin-resistant Staphylococcus pseudintermedius isolates harbor two new staphylococcal cassette chromosome mec (SCCmec) elements that belong to class A, allotype 3 (SCCmec II-III), and to the new allotype 5 (SCCmec VII). Analysis of the complete nucleotide sequences of the topoisomerase loci gyrB/gyrA and grlB/grlA revealed mutations involved in fluoroquinolone resistance.
MeSH terms
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Amino Acid Substitution / genetics
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Animals
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Anti-Bacterial Agents / pharmacology*
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Bacterial Proteins / genetics
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Chromosomes, Bacterial*
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DNA Topoisomerases / genetics
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Dog Diseases / microbiology
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Dogs
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Drug Resistance, Bacterial / genetics*
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Fluoroquinolones / pharmacology*
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Genes, Bacterial*
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Mutation, Missense
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Sequence Analysis, DNA
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Staphylococcal Infections / microbiology
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Staphylococcal Infections / veterinary
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Staphylococcus / drug effects*
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Staphylococcus / genetics*
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Staphylococcus / isolation & purification
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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Fluoroquinolones
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DNA Topoisomerases
Associated data
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GENBANK/AM262967
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GENBANK/AM262968
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GENBANK/AM262969
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GENBANK/AM262970
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GENBANK/AM262971
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GENBANK/AM262972
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GENBANK/AM904731
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GENBANK/AM904732