Abstract
In several forms of human cancer, only a phenotypic subset of cancer cells, usually termed "cancer stem cells" (CSC), can initiate tumor growth when transplanted. In this issue of Cell Stem Cell, Hermann et al. (2007) analyze the relationship between CSC and tumor metastasis.
MeSH terms
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AC133 Antigen
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Animals
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Antigens, CD / metabolism
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Cell Movement
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Cell Proliferation
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Glycoproteins / metabolism
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Humans
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Mice
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Neoplasm Metastasis
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Neoplastic Stem Cells / pathology*
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Pancreatic Neoplasms / pathology
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Peptides / metabolism
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Receptors, CXCR4 / metabolism
Substances
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AC133 Antigen
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Antigens, CD
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Glycoproteins
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Peptides
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Receptors, CXCR4