Cancer stem cells and tumor metastasis: first steps into uncharted territory

Cell Stem Cell. 2007 Sep 13;1(3):241-2. doi: 10.1016/j.stem.2007.08.012.

Abstract

In several forms of human cancer, only a phenotypic subset of cancer cells, usually termed "cancer stem cells" (CSC), can initiate tumor growth when transplanted. In this issue of Cell Stem Cell, Hermann et al. (2007) analyze the relationship between CSC and tumor metastasis.

Publication types

  • Comment

MeSH terms

  • AC133 Antigen
  • Animals
  • Antigens, CD / metabolism
  • Cell Movement
  • Cell Proliferation
  • Glycoproteins / metabolism
  • Humans
  • Mice
  • Neoplasm Metastasis
  • Neoplastic Stem Cells / pathology*
  • Pancreatic Neoplasms / pathology
  • Peptides / metabolism
  • Receptors, CXCR4 / metabolism

Substances

  • AC133 Antigen
  • Antigens, CD
  • Glycoproteins
  • Peptides
  • Receptors, CXCR4