Stuttering priapism--a review of the therapeutic options

Int J Clin Pract. 2008 Aug;62(8):1265-70. doi: 10.1111/j.1742-1241.2008.01780.x. Epub 2008 May 8.

Abstract

Introduction: Priapism is a urological emergency which is commonly classified into low-flow and high-flow priapism. Immediate intervention is required for low-flow cases as the development of ischaemia ultimately leads to long-term erectile dysfunction. Stuttering or recurrent priapism is less well understood. This subtype is characterised by short-lived painful erections and is commonly encountered in patients with sickle cell disease.

Methods: A systematic review of the treatment options available for stuttering priapism is presented combined with our own experience in managing this condition over a period of 25 years.

Results: Although numerous medical treatment options have been reported, the majority are through small trials or anecdotal reports.

Conclusions: Stuttering priapism is a condition which is still not well understood and there is no standardised algorithm for the management of this condition. A multicentre randomised trial is required to evaluate the treatment options.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Anemia, Sickle Cell / complications
  • Digoxin / therapeutic use
  • Drug Delivery Systems / methods
  • Etilefrine / therapeutic use
  • Hormones / therapeutic use*
  • Humans
  • Male
  • Orchiectomy / methods*
  • Penile Prosthesis*
  • Phosphodiesterase Inhibitors / therapeutic use
  • Priapism / etiology
  • Priapism / therapy*
  • Procyclidine / therapeutic use
  • Pseudoephedrine / therapeutic use
  • Terbutaline / therapeutic use
  • Treatment Outcome

Substances

  • Hormones
  • Phosphodiesterase Inhibitors
  • Digoxin
  • Pseudoephedrine
  • Procyclidine
  • Terbutaline
  • Etilefrine