Objective: To evaluate the effect and application value of endoscopic resection in sinonasal inverted papillomas.
Method: In a retrospective study, clinical data of 40 patients underwent transnasal endoscopic approach in Chinese PLA General Hospital from July 1999 to April 2005 were analyzed. Tumor stage according to Krouse was T1: 4, T2: 23, T3: 12, T4: 1, respectively.
Result: All lesions were removed completely and 5 patients received post-operative radiation therapy. There were no serious complications occurred. The follow-up period ranged from 24 to 93 months (mean, 45.1 months). Recurrence rate was 15% (6/40) and the rate of malignant transformation and mortality were 7.5 % (3/40), respectively. Average time to recurrence was 37.3 months.
Conclusion: Endoscopic surgery offers a safe and effective treatment for sinonasal inverted papillomas with a minimally invasion. Thorough removal of the tumor and regular follow-up are the key points for success.