Long-term outcome of vitrectomy for an idiopathic macular hole performed with the use of indocyanine green

J Med Invest. 2008 Aug;55(3-4):283-6. doi: 10.2152/jmi.55.283.

Abstract

Purpose: To evaluate the long-term outcome and safety of vitrectomy for the treatment of an idiopathic macular hole using indocyanine green (ICG) to peel the internal limiting membrane(ILM).

Subjects and methods: By means of a retrospective study, we evaluated the outcomes of 56 eyes in 56 patients with an idiopathic macular hole who all underwent a primary vitrectomy with successful closure of macular hole. We compared the outcomes of 35 eyes in 35 patients who underwent a vitrectomy with ICG-assisted ILM peeling to those of 21 eyes in 21 patients who underwent the same procedure without ILM peeling. The main outcomes were compared between preoperative and postoperative visual acuities.

Results: The periods to achieve the postoperative best visual acuity were 11.1 months in the ILM peeling group and 8.9 months in the non-ILM peeling group. However, there were no significant differences between the two groups regarding the postoperative best visual acuity and the final visual acuity. Complications related to ILM peeling with ICG were not found.

Conclusion: These results support the safety of ILM peeling with ICG.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Coloring Agents* / adverse effects
  • Female
  • Humans
  • Indocyanine Green* / adverse effects
  • Male
  • Middle Aged
  • Retinal Perforations / physiopathology
  • Retinal Perforations / surgery*
  • Retrospective Studies
  • Treatment Outcome
  • Visual Acuity
  • Vitrectomy / methods*

Substances

  • Coloring Agents
  • Indocyanine Green