Evaluation of commercially available anti-dengue virus immunoglobulin M tests

Emerg Infect Dis. 2009 Mar;15(3):436-40. doi: 10.3201/eid1503.080923.

Abstract

Anti-dengue virus immunoglobulin M kits were evaluated. Test sensitivities were 21%-99% and specificities were 77%-98% compared with reference ELISAs. False-positive results were found for patients with malaria or past dengue infections. Three ELISAs showing strong agreement with reference ELISAs will be included in the World Health Organization Bulk Procurement Scheme.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Viral / blood*
  • Dengue / diagnosis*
  • Dengue / virology
  • Dengue Virus / immunology*
  • Enzyme-Linked Immunosorbent Assay
  • False Positive Reactions
  • Humans
  • Immunoglobulin M / blood*
  • Reagent Kits, Diagnostic*
  • Reproducibility of Results
  • Sensitivity and Specificity

Substances

  • Antibodies, Viral
  • Immunoglobulin M
  • Reagent Kits, Diagnostic