A retrospective six-year national survey of P. multocida infections in Israel

Scand J Infect Dis. 2009;41(6-7):445-9. doi: 10.1080/00365540902968035.

Abstract

Pasteurella multocida is the commonest organism infecting pet bites. Anecdotal reports tend to overemphasize dramatic outcomes. We aimed to study a large database of P. multocida infections. This retrospective survey of P. multocida infections in Israeli hospitals refers to the y 2000-2005. Clinical microbiologists were contacted by email and asked to perform a back-search of their hospital's records for isolates of P. multocida. The charts of patients growing P. multocida were abstracted into a structured questionnaire. 77 cases were identified in 12 hospitals, yielding an annual incidence of 0.19/100,000. The mean age was 49.2+/-26.5 y and the mortality rate was 2.6%. Those who died were >65 y of age, had diabetes mellitus or cirrhosis and were bacteraemic. One-third of the cases occurred in people aged > or =65 y. Cats caused most of these infections (54%). Surgery for debridement was common (53.7%), but no-one required amputation; a second- and third-look operation was necessary for these patients. Bacteraemia was found in 32.5% of patients and was significantly more common among those aged >60 y (p =0.044). Hospitalized patients with P. multocida have a favourable prognosis, apart from elderly and bacteraemic patients with comorbidities. Surgery and reoperations may be required in about half of the patients.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Bacteremia / drug therapy
  • Bacteremia / epidemiology
  • Chi-Square Distribution
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Israel / epidemiology
  • Male
  • Middle Aged
  • Pasteurella Infections / diagnosis
  • Pasteurella Infections / drug therapy
  • Pasteurella Infections / epidemiology*
  • Pasteurella multocida / isolation & purification*
  • Retrospective Studies
  • Surveys and Questionnaires

Substances

  • Anti-Bacterial Agents