Ophthalmoplegia and ptosis: mitochondrial toxicity in patients receiving HIV therapy

Neurology. 2009 Jul 7;73(1):71-2. doi: 10.1212/WNL.0b013e3181aae814.
No abstract available

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-HIV Agents / adverse effects
  • Antiretroviral Therapy, Highly Active / adverse effects*
  • Blepharoptosis / chemically induced
  • Blepharoptosis / metabolism
  • Blepharoptosis / physiopathology
  • DNA, Mitochondrial / drug effects
  • Didanosine / adverse effects
  • Genetic Predisposition to Disease / genetics
  • HIV Infections / drug therapy*
  • Humans
  • Lipodystrophy / chemically induced
  • Lipodystrophy / metabolism
  • Lipodystrophy / physiopathology
  • Male
  • Middle Aged
  • Mitochondria / drug effects
  • Mitochondria / metabolism
  • Mitochondria / pathology
  • Mitochondrial Diseases / chemically induced*
  • Mitochondrial Diseases / genetics
  • Mitochondrial Diseases / physiopathology*
  • Muscle, Skeletal / drug effects
  • Muscle, Skeletal / pathology
  • Muscle, Skeletal / physiopathology
  • Mutation / genetics
  • Oculomotor Muscles / drug effects
  • Oculomotor Muscles / pathology
  • Oculomotor Muscles / physiopathology
  • Ophthalmoplegia / chemically induced
  • Ophthalmoplegia / metabolism
  • Ophthalmoplegia / physiopathology
  • Ophthalmoplegia, Chronic Progressive External / chemically induced*
  • Ophthalmoplegia, Chronic Progressive External / metabolism
  • Ophthalmoplegia, Chronic Progressive External / physiopathology*
  • Recovery of Function / physiology
  • Risk Factors
  • Time

Substances

  • Anti-HIV Agents
  • DNA, Mitochondrial
  • Didanosine