Abstract
Human adenovirus (HAdV)-positive nasopharyngeal aspirate preceding hematopoietic stem cell transplantation was prospectively analyzed in 62 patients. By multivariate Cox proportional hazard models, HAdV-positive nasopharyngeal aspirate was the only predictor for HAdV DNAemia after hematopoietic stem cell transplantation (P < .001). HAdV DNAemia was a predictor for alloreactive disease. Early detection and intervention might help to prevent HAdV disease after hematopoietic stem cell transplantation.
MeSH terms
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Adenoviridae Infections / epidemiology*
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Adenoviridae Infections / virology
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Adenoviruses, Human / isolation & purification*
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Adolescent
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Carrier State / epidemiology*
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Carrier State / virology
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Child
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Child, Preschool
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DNA, Viral / isolation & purification
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Female
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Graft Rejection / epidemiology
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Hematopoietic Stem Cell Transplantation / adverse effects*
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Humans
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Infant
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Infant, Newborn
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Male
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Nasopharynx / virology*
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Prevalence
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Prospective Studies
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Risk Factors
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Viremia / epidemiology*
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Viremia / virology
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Young Adult