The "off-label" role of recombinant factor VIIa in surgery: is the problem deficient evidence or defective concept?

J Am Coll Surg. 2009 Nov;209(5):659-67. doi: 10.1016/j.jamcollsurg.2009.07.018. Epub 2009 Sep 19.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Blood Loss, Surgical / prevention & control*
  • Cardiac Surgical Procedures / methods
  • Coagulants / pharmacology
  • Coagulants / therapeutic use*
  • Drug Labeling
  • Factor VIIa / pharmacology
  • Factor VIIa / therapeutic use*
  • Hepatectomy / methods
  • Humans
  • Liver Transplantation / methods
  • Randomized Controlled Trials as Topic
  • Recombinant Proteins / pharmacology
  • Recombinant Proteins / therapeutic use
  • Surgical Procedures, Operative / methods*
  • Surgical Procedures, Operative / trends
  • Traumatology / methods

Substances

  • Coagulants
  • Recombinant Proteins
  • recombinant FVIIa
  • Factor VIIa