Improved results with combined donor-specific transfusion (DST) and sequential therapy protocol

Transplant Proc. 1991 Feb;23(1 Pt 2):1024-6.

Abstract

A combined DST-sequential CyA therapy protocol has been described that results in optimum graft survival for 1- and 2-haplotype mismatched living related donor-recipient combinations. In addition to the excellent graft survival obtained through 4 years, lower prednisone and CyA dosage levels are achieved with significantly decreased infection rates during the posttransplant period.

MeSH terms

  • Blood Transfusion*
  • Communicable Diseases / complications
  • Dose-Response Relationship, Drug
  • Graft Rejection
  • Graft Survival
  • Haplotypes
  • Histocompatibility
  • Humans
  • Hypertension / complications
  • Immunosuppression Therapy / methods*
  • Kidney Transplantation / immunology
  • Kidney Transplantation / methods*
  • Prednisone / administration & dosage
  • Survival Analysis
  • Tissue Donors

Substances

  • Prednisone