[Hepatitis E infection in dialysis and after transplantation]

Nephrol Ther. 2010 Apr;6(2):83-7. doi: 10.1016/j.nephro.2009.10.005. Epub 2010 Jan 21.
[Article in French]

Abstract

Hepatitis E virus (HEV) causes epidemics of acute hepatitis in developing countries, and also appears to be an emerging agent in industrialized countries. HEV infection is transmitted via the fecal-oral route, and may be a zoonosis in industrialized countries. HEV infection was thought to be responsible for acute hepatitis that does not become chronic. However, it has been recently reported that HEV infection can evolve to chronic hepatitis and to cirrhosis, at least in solid-organ transplant patients. The reduction of immunosuppressive drugs could be considered as a first-line therapeutic option.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Developed Countries
  • Developing Countries
  • France / epidemiology
  • Hepatitis E / diagnosis*
  • Hepatitis E / epidemiology*
  • Hepatitis E / transmission
  • Hepatitis E / virology
  • Hepatitis E virus* / isolation & purification
  • Humans
  • Immunocompromised Host*
  • Immunosuppressive Agents / administration & dosage
  • Immunosuppressive Agents / adverse effects*
  • Incidence
  • Kidney Transplantation*
  • Liver Cirrhosis / virology
  • Prevalence
  • Renal Dialysis*

Substances

  • Immunosuppressive Agents