Technology plays a greater and expanding role in the evaluation, diagnosis, and treatment of epilepsy and seizure disorders with the use of electroencephalography and video electroencephalography (EEG) monitoring. However, the history and clinical examination of the patient will always be the most important parts of the evaluation of patients with seizures, epilepsy, and other similar disorders. Clinical pearls for the differential diagnosis of seizures, psychogenic nonepileptic seizures, initial diagnosis of epilepsy, epilepsy evaluation, and use of anticonvulsants are provided.
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