Abstract
We present two cases of invasive infection caused by Streptococcus dysgalactiae subsp. equisimilis, one that showed rapidly developing necrotizing fasciitis in a previously healthy man and one that showed severe cellulitis and septic shock even though the bacterium possessed a mutated emm gene, predicted to encode a truncated M protein.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Antigens, Bacterial / genetics
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Bacterial Outer Membrane Proteins / genetics
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Bacterial Proteins / genetics
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Carrier Proteins / genetics
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Cellulitis / complications
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Cellulitis / microbiology
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DNA, Bacterial / chemistry
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DNA, Bacterial / genetics
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Fasciitis, Necrotizing / microbiology
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Humans
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Male
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Middle Aged
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Molecular Sequence Data
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Mutation
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Sequence Analysis, DNA
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Sequence Deletion
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Shock, Septic / microbiology
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Soft Tissue Infections / microbiology*
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Streptococcal Infections / diagnosis*
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Streptococcal Infections / microbiology
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Streptococcus / classification*
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Streptococcus / genetics
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Streptococcus / isolation & purification*
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Virulence Factors / genetics
Substances
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Antigens, Bacterial
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Bacterial Outer Membrane Proteins
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Bacterial Proteins
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Carrier Proteins
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DNA, Bacterial
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Virulence Factors
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streptococcal M protein
Associated data
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GENBANK/FJ531857
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GENBANK/GQ390354
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GENBANK/GQ390355
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GENBANK/GQ390356
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GENBANK/GQ390357
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GENBANK/GQ845001