Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment

Leukemia. 2010 Apr;24(4):903-7. doi: 10.1038/leu.2010.14. Epub 2010 Feb 18.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Chromosome Breakpoints*
  • Cohort Studies
  • DNA-Binding Proteins / genetics
  • Enzyme Inhibitors / pharmacology
  • Female
  • Histone-Lysine N-Methyltransferase
  • Humans
  • Infant
  • Male
  • Myeloid-Lymphoid Leukemia Protein / genetics*
  • Nuclear Proteins / genetics
  • Oncogene Proteins, Fusion / genetics*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / mortality
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology
  • Pregnancy
  • Prenatal Exposure Delayed Effects
  • Recombination, Genetic
  • Survival Rate
  • Topoisomerase II Inhibitors
  • Transcriptional Elongation Factors

Substances

  • DNA-Binding Proteins
  • Enzyme Inhibitors
  • KMT2A protein, human
  • Nuclear Proteins
  • Oncogene Proteins, Fusion
  • Topoisomerase II Inhibitors
  • Transcriptional Elongation Factors
  • Myeloid-Lymphoid Leukemia Protein
  • AFF1 protein, human
  • Histone-Lysine N-Methyltransferase