Functionalized carbon nanotubes for potential medicinal applications

Drug Discov Today. 2010 Jun;15(11-12):428-35. doi: 10.1016/j.drudis.2010.04.005. Epub 2010 May 6.

Abstract

Functionalized carbon nanotubes display unique properties that enable a variety of medicinal applications, including the diagnosis and treatment of cancer, infectious diseases and central nervous system disorders, and applications in tissue engineering. These potential applications are particularly encouraged by their ability to penetrate biological membranes and relatively low toxicity. High aspect ratio, unique optical property and the likeness as small molecule make carbon nanotubes an unusual allotrope of element carbon. After functionalization, carbon nanotubes display potentials for a variety of medicinal applications, including the diagnosis and treatment of cancer, infectious diseases and central nervous system disorders, and applications in tissue engineering. These potential applications are particularly encouraged by their ability to penetrate biological membranes and relatively low toxicity.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Central Nervous System Diseases / diagnosis
  • Central Nervous System Diseases / drug therapy
  • Communicable Diseases / diagnosis
  • Communicable Diseases / drug therapy
  • Drug Carriers / adverse effects
  • Drug Carriers / chemistry*
  • Drug Delivery Systems*
  • Humans
  • Nanotubes, Carbon / adverse effects
  • Nanotubes, Carbon / chemistry*
  • Neoplasms / diagnosis
  • Neoplasms / drug therapy
  • Tissue Engineering / methods

Substances

  • Drug Carriers
  • Nanotubes, Carbon